Semax is a peptide derived from a fragment of the adrenocorticotropic hormone (ACTH₄₋₁₀) and is primarily studied for its neuroprotective and cognitive-enhancing properties. It works by increasing levels of brain-derived neurotrophic factor (BDNF), supporting neurotransmitter regulation, especially dopamine and serotonin, as well as reducing inflammation and oxidative stress within neural tissue. In research settings, Semax is sometimes administered via subcutaneous or intramuscular injection to promote systemic absorption and potential neuroprotective effects. Studies suggest Semax has the ability to enhance focus, memory, learning capacity, and recovery from neurological or ischemic injury.
Semax
Dosing Guidance
The standard daily dose of Semax ranges from 0.5 mg - 1 mg. Usually, 0.5 mg doses are administered from weeks 1-4, increasing to 1 mg doses for weeks 5-8. This approach is popular for general cognitive support or mild neuroprotection.
An advanced daily dose of
6 mg per day is sometimes referenced in post-stroke settings. This is an aggressive 10-day protocol.
Standard Dosing Protocol:
0.5mg-1mg, 1x Daily, 4-8 Weeks
Reconstitute with 3 mL of bacteriostatic water to create a solution of about 3.33 mg/mL (≈33 mcg per unit).
1. Draw 3.0 mL of bacteriostatic water into a sterile syringe.
2. Inject the water slowly along the vial wall to reduce foam.
3. Gently swirl/roll the vial, avoid vigorous shaking.
4. To store, refrigerate the reconstituted solution at 2–8 °C, protected from light.
Advanced Dosing Protocol:
6 mg, 1x Daily, 10-Day Protocol
Reconstitute with 1 mL to create a 10 mg/mL solution (≈100 mcg per unit).
1. Draw 2mL of bacteriostatic water into a sterile syringe.
2. Inject the water slowly along the vial wall to reduce foam.
3. Gently swirl/roll the vial, avoid vigorous shaking.
4. To store, refrigerate the reconstituted solution at 2–8 °C, protected from light.
Note: If more than 10 mg per day are required, multiple injections or additional vials may be needed.